Molecular Link between Obesity and Type 2 Diabetes Reveals Potential Therapy
- Details
- Written by Heather Buschman, PhD
- Category: Health News
San Diego, California - Obesity causes inflammation, which can in turn lead to type 2 diabetes. What isn’t well established is how inflammation causes diabetes - or what we can do to stop it. Researchers at University of California, San Diego School of Medicine have discovered that the inflammatory molecule LTB4 promotes insulin resistance, a first step in developing type 2 diabetes. What’s more, the team found that genetically removing the cell receptor that responds to LTB4, or blocking it with a drug, improves insulin sensitivity in obese mice. The study is published Feb. 23 by Nature Medicine.
Cutting-edge technology optimizes cancer therapy with nanomedicine drug combinations
- Details
- Written by Brianna Aldrich
- Category: Health News
Los Angeles, California - In greater than 90 percent of cases in which treatment for metastatic cancer fails, the reason is that the cancer is resistant to the drugs being used. To treat drug-resistant tumors, doctors typically use multiple drugs simultaneously, a practice called combination therapy. And one of their greatest challenges is determining which ratio and combination - from the large number of medications available - is best for each individual patient.
Poor response to cholesterol drugs may indicate blocked arteries
- Details
- Written by Akeem Ranmal
- Category: Health News
Dallas, Texas - If your “bad” cholesterol level stays the same or increases after you take statin drugs, you may have more blocked arteries than people whose levels drop, according to research in the American Heart Association journal Arteriosclerosis, Thrombosis and Vascular Biology.
Master Gene Regulatory Pathway Revealed as Key Target for Therapy of Aggressive Pediatric Brain Cancer
- Details
- Written by Johns Hopkins
- Category: Health News
Baltimore, Maryland - Working with cells taken from children with a very rare but ferocious form of brain cancer, Johns Hopkins Kimmel Cancer Center scientists have identified a genetic pathway that acts as a master regulator of thousands of other genes and may spur cancer cell growth and resistance to anticancer treatment.
Molecule hijacks enzyme to boost alcohol metabolism
- Details
- Written by IVN
- Category: Health News
Washington, DC - An experimental compound empowers an enzyme to help process acetaldehyde, a toxic metabolite of alcohol, according to new research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The findings, now online in the Proceedings of the National Academy of Sciences (PNAS), might lead to new treatments to help people with impaired ability to metabolize acetaldehyde and other toxic substances. NIAAA is part of the National Institutes of Health.
Alternative cancer treatments: 10 options to consider
- Details
- Written by Mayo Clinic Staff
- Category: Health News
Scottsdale, Arizona - Many people with cancer are interested in trying anything that may help them, including complementary and alternative cancer treatments. If cancer makes you feel as if you have little control over your health, alternative cancer treatments may offer some feeling of control. But many alternative cancer treatments are unproved and some may even be dangerous.
Page 3209 of 3785