Washington, DC - A one-month antibiotic regimen to prevent active tuberculosis (TB) disease was at least as safe and effective as the standard nine-month therapy for people living with HIV, according to the results of a large international clinical trial. Adults and adolescents in the trial were more likely to complete the short-course regimen - consisting of daily doses of the antibiotics rifapentine and isoniazid for four weeks than the standard nine-month regimen of daily isoniazid.

Washington, DC - Researchers have found that temporarily increasing the dosage of inhaled steroids when asthma symptoms begin to worsen does not effectively prevent severe flare-ups, and may be associated with slowing a child’s growth, challenging a common medical practice involving children with mild-to-moderate asthma.

Cambridge, Massachusetts - Pharmaceutical companies once considered a protein called p38 a very attractive target for treating rheumatoid arthritis. Arthritis patients usually have elevated activity of this inflammation-producing protein, and in lab studies p38 inhibitors appeared to soothe inflammation. However, these drugs failed in several clinical trials.

Phoenix, Arizona - When first diagnosed with cancer, many people ask about their prognosis. You might want to know whether your cancer is relatively easy or more difficult to cure. Your doctor can't predict the future, but can make an estimate based on other people's experiences with the same cancer.

Dallas, Texas - An international study suggests other aspects of the diet may not offset the harmful effect of sodium on blood pressure. The study, published in the American Heart Association’s journal Hypertension, also reaffirms the need for widespread sodium reduction in the food supply.

Scottsdale, Arizona - If you tend to get cold symptoms that develop suddenly and occur at the same time every year, you might have seasonal allergies. Although colds and allergies share some symptoms, they are very different.